NishiNishi Labs

How to order at Domino's on a GLP-1

The least-bad ways to have pizza and the picks to save for a treat, built from Domino's own published US nutrition and Nishi's transparent GLP-1 scoring lens.

The move

Order a thin crust, hold it to two or three slices, load the veggies and a lean protein like grilled chicken or ham, and add a side salad instead of a second pizza.

The quick take

Pizza is carb- and sodium-heavy, and it's honest to treat Domino's as a treat you order carefully rather than a staple. The one move that matters most is the crust: a whole medium Crunchy Thin has about 600 calories and 80 g of carbs from the dough versus roughly 880 calories and 168 g for a Hand Tossed, so thin crust nearly halves the carb load. From there, choose lean toppings (premium grilled chicken, ham, and any of the veggies) over the meat stacks, and keep it to two or three slices. If you want to skip the dough entirely, the Chicken Caesar salad is 220 calories for 19 g of protein and boneless chicken is 170 for 9 g. The traps are the Pan and stuffed crusts, the meat-loaded specialties (ExtravaganZZa, MeatZZa, Spicy Chicken Bacon Ranch), the wings and dipping cups, and sodium everywhere, which runs 700 to 1,300 mg on a single specialty slice-serving.

The menu, scored

Order one as-is. Scored for whole meals, a gentler bar than the single ingredients above, since a balanced meal is naturally less protein-dense and fat only counts against it once it tops half the calories. Best fit first; tap "Show the math" to see the exact rule on any card. How we score.
Chicken Caesar SaladGood fit
19 g protein · 220 cal · 14 g carbs · 8 g fat · 2 g fiber
19 g protein · lots of protein for the calories · lower fat
Show the math
Protein19 gstrong at 30 g or morebelow 30 g
Protein density8.6 g per 100 kcalstrong at 7.5+, weak under 4strong
Fat32.7% of caloriesflag over 50% or friedok
Fiber2 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density220 kcalflag if density under 4 and 300 kcal or moreok
Sodium490 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Chicken Parm Sandwich (1/2)Good fit
24 g protein · 400 cal · 38 g carbs · 15 g fat · 0 g fiber
24 g protein · lower fat
Show the math
Protein24 gstrong at 30 g or morebelow 30 g
Protein density6 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat33.8% of caloriesflag over 50% or friedok
Fiber0 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density400 kcalflag if density under 4 and 300 kcal or moreok
Sodium1050 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Boneless Chicken (3 pc)Good fit
9 g protein · 170 cal · 18 g carbs · 7 g fat · 0 g fiber
9 g protein · lower fat
Show the math
Protein9 gstrong at 30 g or morebelow 30 g
Protein density5.3 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat37.1% of caloriesflag over 50% or friedok
Fiber0 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density170 kcalflag if density under 4 and 300 kcal or moreok
Sodium660 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Buffalo Chicken Sandwich (1/2)Good fit
20 g protein · 420 cal · 39 g carbs · 20 g fat · 0 g fiber
watch: 1300 mg sodium
Show the math
Protein20 gstrong at 30 g or morebelow 30 g
Protein density4.8 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat42.9% of caloriesflag over 50% or friedok
Fiber0 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density420 kcalflag if density under 4 and 300 kcal or moreok
Sodium1300 mginformational over 1200 mgshown; does not change the tier

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Honolulu Hawaiian Pizza (medium slice)Good fit
17 g protein · 380 cal · 40 g carbs · 17 g fat · 1 g fiber
17 g protein · lower fat
Show the math
Protein17 gstrong at 30 g or morebelow 30 g
Protein density4.5 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat40.3% of caloriesflag over 50% or friedok
Fiber1 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density380 kcalflag if density under 4 and 300 kcal or moreok
Sodium910 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Memphis BBQ Chicken Pizza (medium slice)Good fit
18 g protein · 410 cal · 44 g carbs · 17 g fat · 1 g fiber
18 g protein · lower fat
Show the math
Protein18 gstrong at 30 g or morebelow 30 g
Protein density4.4 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat37.3% of caloriesflag over 50% or friedok
Fiber1 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density410 kcalflag if density under 4 and 300 kcal or moreok
Sodium800 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

MeatZZa Pizza (medium slice)Good fit
18 g protein · 420 cal · 38 g carbs · 21 g fat · 1 g fiber
18 g protein · lower fat
Show the math
Protein18 gstrong at 30 g or morebelow 30 g
Protein density4.3 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat45% of caloriesflag over 50% or friedok
Fiber1 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density420 kcalflag if density under 4 and 300 kcal or moreok
Sodium1000 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Spinach & Feta Pizza (medium slice)Good fit
15 g protein · 370 cal · 37 g carbs · 17 g fat · 1 g fiber
15 g protein · lower fat
Show the math
Protein15 gstrong at 30 g or morebelow 30 g
Protein density4.1 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat41.4% of caloriesflag over 50% or friedok
Fiber1 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density370 kcalflag if density under 4 and 300 kcal or moreok
Sodium710 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Philly Cheese Steak Pizza (medium slice)Good fit
15 g protein · 370 cal · 37 g carbs · 16 g fat · 1 g fiber
15 g protein · lower fat
Show the math
Protein15 gstrong at 30 g or morebelow 30 g
Protein density4.1 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat38.9% of caloriesflag over 50% or friedok
Fiber1 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density370 kcalflag if density under 4 and 300 kcal or moreok
Sodium890 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

ExtravaganZZa Pizza (medium slice)Good fit
18 g protein · 440 cal · 40 g carbs · 22 g fat · 2 g fiber
18 g protein · lower fat
Show the math
Protein18 gstrong at 30 g or morebelow 30 g
Protein density4.1 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat45% of caloriesflag over 50% or friedok
Fiber2 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density440 kcalflag if density under 4 and 300 kcal or moreok
Sodium1040 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Ultimate Pepperoni Pizza (medium slice)Good fit
17 g protein · 420 cal · 38 g carbs · 21 g fat · 1 g fiber
17 g protein · lower fat
Show the math
Protein17 gstrong at 30 g or morebelow 30 g
Protein density4 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat45% of caloriesflag over 50% or friedok
Fiber1 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density420 kcalflag if density under 4 and 300 kcal or moreok
Sodium960 mginformational over 1200 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Hot Buffalo Wings (4 pc)Lower fit
15 g protein · 260 cal · 9 g carbs · 20 g fat · 0 g fiber
watch: higher fat (69.2% of calories), 1520 mg sodium
Show the math
Protein15 gstrong at 30 g or morebelow 30 g
Protein density5.8 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat69.2% of caloriesflag over 50% or friedflagged
Fiber0 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density260 kcalflag if density under 4 and 300 kcal or moreok
Sodium1520 mginformational over 1200 mgshown; does not change the tier

Lower fit. Flagged on fat without both strong protein and strong density. These published rules are applied the same way to every item scored on this bar; see how we score.

Plain Wings (4 pc)Lower fit
14 g protein · 250 cal · 8 g carbs · 20 g fat · 0 g fiber
watch: higher fat (72% of calories)
Show the math
Protein14 gstrong at 30 g or morebelow 30 g
Protein density5.6 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat72% of caloriesflag over 50% or friedflagged
Fiber0 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density250 kcalflag if density under 4 and 300 kcal or moreok
Sodium720 mginformational over 1200 mgok

Lower fit. Flagged on fat without both strong protein and strong density. These published rules are applied the same way to every item scored on this bar; see how we score.

Spicy Chicken Bacon Ranch Pizza (medium slice)Lower fit
19 g protein · 480 cal · 38 g carbs · 27 g fat · 1 g fiber
watch: higher fat (50.6% of calories), 1280 mg sodium
Show the math
Protein19 gstrong at 30 g or morebelow 30 g
Protein density4 g per 100 kcalstrong at 7.5+, weak under 4moderate
Fat50.6% of caloriesflag over 50% or friedflagged
Fiber1 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density480 kcalflag if density under 4 and 300 kcal or moreok
Sodium1280 mginformational over 1200 mgshown; does not change the tier

Lower fit. Flagged on fat without both strong protein and strong density. These published rules are applied the same way to every item scored on this bar; see how we score.

Pacific Veggie Pizza (medium slice)Lower fit
14 g protein · 360 cal · 39 g carbs · 15 g fat · 2 g fiber
watch: energy-dense, low protein
Show the math
Protein14 gstrong at 30 g or morebelow 30 g
Protein density3.9 g per 100 kcalstrong at 7.5+, weak under 4low density
Fat37.5% of caloriesflag over 50% or friedok
Fiber2 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density360 kcalflag if density under 4 and 300 kcal or moreflagged
Sodium730 mginformational over 1200 mgok

Lower fit. Protein density is under 4 g per 100 kcal, which is fundamentally low when appetite is limited. These published rules are applied the same way to every item scored on this bar; see how we score.

Classic Garden SaladLower fit
3 g protein · 80 cal · 8 g carbs · 4 g fat · 1 g fiber
3 g protein · lower fat
Show the math
Protein3 gstrong at 30 g or morebelow 30 g
Protein density3.8 g per 100 kcalstrong at 7.5+, weak under 4low density
Fat45% of caloriesflag over 50% or friedok
Fiber1 greward 5+, flag over 30ok
Added sugarnot published by the restaurantflag over 30 gnot scored
Portion density80 kcalflag if density under 4 and 300 kcal or moreok
Sodium125 mginformational over 1200 mgok

Lower fit. Protein density is under 4 g per 100 kcal, which is fundamentally low when appetite is limited. These published rules are applied the same way to every item scored on this bar; see how we score.

Best proteins to build around

GLP-1 fit is Nishi's score, not the restaurant's. How we score.

Numbers are for one published serving as Domino's lists it. Pizza serving size differs by crust and size: a 12" medium is 1/8 of the pizza on Hand Tossed and Pan, 1/6 on New York Style, and 1/4 on Crunchy Thin. Specialty pizzas below are one medium slice (1/5 of the pizza) as published. Non-pizza items use Domino's stated serving (piece count, container, or 1/2 sandwich). Gram weights are published.. Tap "Show the math" on any pick to see exactly how its rating was calculated.

Premium ChickenGood fit
2 g protein · 20 cal · 0.5 g fat · 70 mg sodium
2 g protein · lots of protein for the calories · lower fat
Show the math
Protein2 gstrong at 25 g or morebelow 25 g
Protein density10 g per 100 kcalstrong at 10+, weak under 6strong
Fat22.5% of caloriesflag over 37.5% or friedok
Fiber0 greward 5+, flag over 18ok
Added sugarnot published by the restaurantflag over 17 gnot scored
Portion density20 kcalflag if density under 6 and 300 kcal or moreok
Sodium70 mginformational over 800 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

Philly SteakGood fit
1 g protein · 15 cal · 0.5 g fat · 100 mg sodium
1 g protein · lower fat
Show the math
Protein1 gstrong at 25 g or morebelow 25 g
Protein density6.7 g per 100 kcalstrong at 10+, weak under 6moderate
Fat30% of caloriesflag over 37.5% or friedok
Fiber0 greward 5+, flag over 18ok
Added sugarnot published by the restaurantflag over 17 gnot scored
Portion density15 kcalflag if density under 6 and 300 kcal or moreok
Sodium100 mginformational over 800 mgok

Good fit. Solid, but not the full combination of strong protein, strong density, and no flags, so it sits in the middle. These published rules are applied the same way to every item scored on this bar; see how we score.

HamLower fit
1 g protein · 10 cal · 0.5 g fat · 125 mg sodium
watch: higher fat (45% of calories)
Show the math
Protein1 gstrong at 25 g or morebelow 25 g
Protein density10 g per 100 kcalstrong at 10+, weak under 6strong
Fat45% of caloriesflag over 37.5% or friedflagged
Fiber0 greward 5+, flag over 18ok
Added sugarnot published by the restaurantflag over 17 gnot scored
Portion density10 kcalflag if density under 6 and 300 kcal or moreok
Sodium125 mginformational over 800 mgok

Lower fit. Flagged on fat without both strong protein and strong density. These published rules are applied the same way to every item scored on this bar; see how we score.

BaconLower fit
3 g protein · 45 cal · 3.5 g fat · 160 mg sodium
watch: higher fat (70% of calories)
Show the math
Protein3 gstrong at 25 g or morebelow 25 g
Protein density6.7 g per 100 kcalstrong at 10+, weak under 6moderate
Fat70% of caloriesflag over 37.5% or friedflagged
Fiber0 greward 5+, flag over 18ok
Added sugarnot published by the restaurantflag over 17 gnot scored
Portion density45 kcalflag if density under 6 and 300 kcal or moreok
Sodium160 mginformational over 800 mgok

Lower fit. Flagged on fat without both strong protein and strong density. These published rules are applied the same way to every item scored on this bar; see how we score.

BeefLower fit
2 g protein · 40 cal · 3.5 g fat · 90 mg sodium
watch: higher fat (78.8% of calories)
Show the math
Protein2 gstrong at 25 g or morebelow 25 g
Protein density5 g per 100 kcalstrong at 10+, weak under 6low density
Fat78.8% of caloriesflag over 37.5% or friedflagged
Fiber0 greward 5+, flag over 18ok
Added sugarnot published by the restaurantflag over 17 gnot scored
Portion density40 kcalflag if density under 6 and 300 kcal or moreok
Sodium90 mginformational over 800 mgok

Lower fit. Protein density is under 6 g per 100 kcal, which is fundamentally low when appetite is limited. These published rules are applied the same way to every item scored on this bar; see how we score.

Italian SausageLower fit
2 g protein · 50 cal · 4.5 g fat · 80 mg sodium
watch: higher fat (81% of calories)
Show the math
Protein2 gstrong at 25 g or morebelow 25 g
Protein density4 g per 100 kcalstrong at 10+, weak under 6low density
Fat81% of caloriesflag over 37.5% or friedflagged
Fiber0 greward 5+, flag over 18ok
Added sugarnot published by the restaurantflag over 17 gnot scored
Portion density50 kcalflag if density under 6 and 300 kcal or moreok
Sodium80 mginformational over 800 mgok

Lower fit. Protein density is under 6 g per 100 kcal, which is fundamentally low when appetite is limited. These published rules are applied the same way to every item scored on this bar; see how we score.

PepperoniLower fit
1 g protein · 30 cal · 2.5 g fat · 125 mg sodium
watch: higher fat (75% of calories)
Show the math
Protein1 gstrong at 25 g or morebelow 25 g
Protein density3.3 g per 100 kcalstrong at 10+, weak under 6low density
Fat75% of caloriesflag over 37.5% or friedflagged
Fiber0 greward 5+, flag over 18ok
Added sugarnot published by the restaurantflag over 17 gnot scored
Portion density30 kcalflag if density under 6 and 300 kcal or moreok
Sodium125 mginformational over 800 mgok

Lower fit. Protein density is under 6 g per 100 kcal, which is fundamentally low when appetite is limited. These published rules are applied the same way to every item scored on this bar; see how we score.

Go easy on

Common questions

What's the best crust to order at Domino's on a GLP-1?

Thin crust. A whole medium Crunchy Thin has about 600 calories and 80 g of carbs from the dough, while a Hand Tossed is roughly 880 calories and 168 g, so thin crust nearly halves the carb load. A Hand Tossed slice is 110 calories; a Pan slice jumps to 190.

What are the leanest toppings at Domino's?

Premium grilled chicken, ham, and any of the vegetables. Per slice, premium chicken adds 20 calories for 2 g of protein and ham 10 calories, while the veggies (peppers, onions, mushrooms, spinach) are near zero. The fatty adds are sausage, bacon, and beef.

Which specialty pizza is the lighter pick?

Pacific Veggie is the leanest specialty at 360 calories a medium slice, and Spinach & Feta is 370. Memphis BBQ Chicken is 410 with 18 g of protein. Keep it to two or three slices, since the numbers are per single slice.

What should I get instead of a whole pizza?

The Chicken Caesar salad is 220 calories for 19 g of protein with no bread, and boneless chicken is 170 calories for 9 g over three pieces. Both skip the dough entirely while keeping the protein.

How high is the sodium at Domino's?

High across the board. A single specialty slice runs 700 to 1,300 mg, Hot Buffalo Wings are 1,520 mg for four pieces, and the oven-baked sandwiches are 1,050 to 1,300 mg a half. Thin crust and lean toppings keep it lower, but pizza is a high-sodium food, so watch the sides.

Why you can trust this

  • Where the numbers come from. Domino's official US Nutrition Guide (PDF), last verified 2026-07-23. We publish only values the restaurant itself publishes.
  • How each score is calculated. Deterministic rules published in full in our methodology (v1.1), with one published bar for single ingredients and one for whole meals. Every row above lists the exact factors behind its label.
  • What the score does and does not consider. See the limitations. It scores one item, not your whole day, and it is not medical advice.
  • How to challenge or correct it. Tell us if a value is stale or a call looks wrong. Corrections are recorded in the methodology version history.

More restaurant guides

The same transparent scoring, applied to other chains. See all restaurants.

Explore more

Cross-chain picks and head-to-heads, scored the same published way.
Get this for any meal, personalizedNishi scores your exact order and remembers your goals.
Open in the Nishi app